Scientist III

Scientist III
$52 - $55/hr medical benefits available at a cost.
1 year initial contract with possibility of extension
100% onsite in North Chicago, IL
Standard first shift business hours M-F

Orion Group and a market leading pharmaceutical company are teaming up once again for a new contract opportunity for Pharmaceutical Scientists in North Chicago, IL!

Our client is seeking candidates with prior experience supporting and driving process development activities for NBEs (New Biologic Entities). Apply today and take the first step towards your next career opportunity!!

Job Description:
The pharmaceutical development group for new biological entities (NBEs) develops antibody drug conjugates (ADC) and other biologics by state of the art formulation, processing and analytical technologies. We create intellectual property through new formulation compositions, lean and smart manufacturing processes and prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content.

We are looking for a highly motivated person who supports and drives process development activities for NBEs. The candidate will maintain as well as improve our technological equipment to expand the state-of-the-art and support the development of manufacturing processes for biologics. Furthermore, the candidate will keep and increase the state of operational excellence of our lab. Working closely with analytical and formulation scientists in an integrated group the candidate will develop productive collaborations and communications with scientific and technical teams.

Major Responsibilities:

• Supporting the process development of parenteral formulations for biologics with a focus on antibody drug conjugates.
• Design and execute studies evaluating the stability (chemical & physical) of biologics against solution conditions (pH, ionic strength, temperature, light, moisture, etc.) and physical stresses arising from manufacturing process conditions (freeze thaw, mixing, filtration, filling, and lyophilization), and screen excipients (buffers, stabilizers, surfactants, etc.) to develop robust formulations for frozen, refrigerated liquid, and lyophilized dosage forms.
• Being the first point of contact for the operation of advanced NBE process technologies with special emphasis on process unit operation (filling, filtration, lyophilization)
• Continuous thorough maintenance (mechanical, electrical) of process and laboratory development equipment and troubleshooting of technical issues on the machines.
• Builds strong relationships to other functional units (e.g. S&T, combination products, Analytical Development) and supports activities in collaboration with partners.
• Optimize laboratory operations for efficient use of time and resources.
• Document experimental data thoroughly in lab documentation systems, make concise scientific presentations of process results and author detailed scientific technical reports.
• Understand and adhere to corporate standards regarding code of conduct, safety, and GXP compliance.

Qualifications:

• BS or MS in Chemistry, Pharmaceutical, biological, engineering, food science or related discipline with typically 4(BS) or 0-2 (MS) years of relevant experience. or significant technical / industrial experience in the technical field.
• Solid understanding of the various unit operations of aseptic manufacturing such as bulk freeze thaw, compounding/mixing, filtration, filling, and lyophilization for liquid and lyophilized NBEs.
• Experience with process development of parenteral formulations for biologics with a focus on antibody drug conjugates.
• Experienced in laboratory systems (ELN) preferred.
• Experience in Microsoft Office (Excel, Sharepoint, PowerPoint, and Word) required.

Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.