Scientist I - (Quantitative LC-MS/MS Bioanalysis)

Scientist I (Quantitative LC-MS/MS Bioanalysis)
Rate: $38 - $42/hr with medical benefits available at a cost
Contract length: 6 month initial contract with possibility of extensions up to 2 years
Location: 100% Onsite in North Chicago, IL
Shift: Monday – Friday 8 am to 5 pm

Orion Project Services has teamed up again with a market-leading pharmaceutical company for an exciting contract opportunity for a Scientist I specializing in quantitative LC-MS/MS bioanalysis.

Based onsite in North Chicago, IL, you will support innovative research and development projects by performing quantitative LC-MS/MS analysis of synthetic molecules and peptides for ADME bioassays and PK/PD studies. You will also analyze and interpret data, troubleshoot and maintain instrumentation, and document your work using electronic laboratory notebooks.

This opportunity is ideal for an early-career scientist with a bachelor’s or master’s degree in chemistry, biology, pharmacology, or a related field who has hands-on LC-MS/MS experience and enjoys working in a collaborative, fast-paced laboratory environment.

Job Description:
The Quantitative, Translational, and ADME Sciences Department in North Chicago, IL is seeking a highly motivated team member to operate in an LCMS-based quantitative bioanalytical role to support research and development projects.

The successful candidate will be in a fast-paced, dynamic environment with minimal supervision once trained. The candidate will be responsible for quantitative LC-MS/MS bioanalysis of synthetic molecules and peptides, data analysis and interpretation, and documentation.

Key Responsibilities:

• Perform quantitative LC-MS/MS of synthetic molecules and peptides from in-vitro and in-vivo biomatrices to support ADME bioassays and PK/PD studies.
• Operate and troubleshoot LC-MS/MS instrumentation and perform routine maintenance of LC-MS/MS equipment.
• Maintain excellent documentation of all work, including electronic lab notebooks, methods, and protocols.

Qualifications:

• Bachelor’s degree in a scientific field (e.g., chemistry, biology, pharmacology, or related disciplines), with typically 0-3 years of experience, or a master’s degree with no additional experience.
• Experience with quantitative bioanalysis of synthetic molecules and peptides.
• Hands-on experience with one or more current LC-MS/MS platforms (e.g., Sciex triple quadrupoles, Agilent HPLCs, Shimadzu HPLCs, PAL autosamplers, ADDA, LS-II) and software (e.g., Analyst, Discovery Quant, LeadScape, Sciex OS, Electronic Laboratory Notebook).
• Familiarity with automated sample preparation platforms.
• Familiarity with ADME, PK, PD, and bioassays.
• A good understanding of analytical methodologies used for synthetic molecules and peptide quantitation (acquisition, processing, and troubleshooting).
• Ability to work independently or under minimal supervision to conduct experiments, as well as interpret, document, and communicate results.
• Ability to balance generating high quality data within a standardized, streamlined, and high-throughput environment.
• Ability to work effectively with team members in a dynamic environment, self-motivate, multitask, meet frequent tight deadlines, and adapt to changing priorities.

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