23265 MS&T Scientist
CR/077582
Posted: 13/05/2025
- Competitive
- Ireland, County Meath
- Contract
Orion Group Life Sciences are currently recruiting an MS&T Scientist (Upstream) on behalf of our Multinational Biopharmaceutical Client based in Meath on an initial 11-Month contract with potential to extend.
Job Purpose
This role is part of the Manufacturing Science and Technology (MS&T) hub at our state-of-the-art, single-use, multi-product facility.
Educational and experience requirements
Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
- This role is site and lab-based
- Approximately 1x weekend shift per month required (days)
Job Purpose
This role is part of the Manufacturing Science and Technology (MS&T) hub at our state-of-the-art, single-use, multi-product facility.
- The MS&T Scientist (Specialist) is responsible for contributing to the overall running of the MS&T Bioprocess Laboratory and working across site as part of a diverse and interdisciplinary team to build capability and knowledge in the manufacture of biologics.
- Key responsibilities of the MS&T Scientist include the planning and execution of scale-down model establishment in upstream/downstream, analytical testing, satellite and improvement studies in the MS&T Bioprocess Lab, and the provision of technical expertise and leadership to support successful new product introduction.
- Plan and execute upstream activities (USP) for scale-down model establishments, satellite runs and investigation/improvement studies in the MS&T lab (i.e. vial thaws, shake flask passaging, benchtop bioreactor operations including inoculation, sampling, feeding and harvest)
- Support the transfer of new products (NPI) into the MS&T laboratory
- Provide upstream specialist support to the site and the network for non-routine analysis and troubleshooting
- Experimental design, execution, data analysis and interpretation through DOEs
- Author and review standard operating procedures and technical reports
- Support multidisciplinary teams (MS&T, quality, analytics, regulatory) for process improvement and troubleshooting
- Assure effective application of Lean Six Sigma and Change Management tools in the MS&T lab team by:
- Securing continuity of an appropriate level of knowledge
- Facilitating problem-solving and risk assessment (FMEA) projects/meetings
- Making problems visible and striving for continuous improvement
- Serve as an upstream specialist during internal audits and external inspections/audits
- Support alignment and knowledge exchange with development organizations, other commercial nodes and external manufacturing partners
- Lead and coach others to solve problems and take new perspectives on existing solutions with a desire to continuously learn, improve and develop
- Demonstrate excellent troubleshooting and problem-solving skills, as well as influencing, collaboration skills and teamworking ability to represent MS&T on global and interdisciplinary teams
- Complete product robustness monitoring in partnership with global technical teams and provide leadership for investigations
- Demonstrate a “safety first, quality always” mindset in all responsibilities
Educational and experience requirements
- Bachelor of Science degree with a minimum of 5 years of experience, Master of Science with a minimum of 3 years, or PhD in a scientific discipline (biotechnology, biochemistry, pharmacy, process engineering or equivalent)
- Technical expertise with biologics drug substance upstream and downstream operations, analytical testing, process development, and tech transfer
- Proven ability to work both independently and collaboratively
- Logical thinking and proactive under pressure
- Effective communicator with deep technical expertise
- Proven ability to work cross-functionally, track to schedules, and embrace an interdependent work culture
- Experience working in a GMP/regulated environment is desirable
- Strong organizational skills – ability to manage multiple priorities and escalate issues when necessary
Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
Aoibhinn Daly
Recruitment Consultant
Apply for this role
Recruitment